Empowering Parkinson’s Research: Advanced Hand Kinematics Analysis with flexible PCBs

A groundbreaking sensor glove for Parkinson's disease, developed by Changchun University and UCLA, uses LPKF’s ProtoLaser U4 for precise PCB fabrication, offering new insights for diagnosis and treatment.

Parkinson's disease (PD), the fastest-growing neurodegenerative disorder worldwide, severely impacts the quality of life for millions. Hand dysfunction — manifesting as tremors, rigidity, and muscle weakness — can be debilitating for patients. However, clinicians and researchers have long faced challenges in developing objective and comprehensive assessment tools.
A groundbreaking study led by researchers from Changchun University of Science and Technology and UCLA has introduced a multimodal sensor glove capable of revolutionizing hand function assessment.  

Part of this innovation was LPKF’s ProtoLaser U4, which played a critical role in the precise fabrication of the glove’s flexible printed circuit board (PCB). The result is a wearable device that not only gathers important hand kinematics data but also translates it into actionable insights for rehabilitation and treatment. 

Why This Research Matters 

Parkinson’s disease affects over 10 million people globally, with its prevalence expected to rise. Tools like a multimodal sensor glove not only enhance our understanding of PD but also provide scalable solutions to support patient care and research. The reliable data produced by this special glove could help clinicians design targeted treatments, while researchers explore novel therapies.  

A Wearable Revolution in Parkinson’s Diagnostics 

The multimodal sensor glove leverages cutting-edge flexible sensors to measure hand bending angles, muscle strength, and tremor stability. By combining these data streams with sophisticated algorithms — including Back Propagation Neural Networks (BPNN) — the glove achieves a remarkable tremor classification accuracy of 95.83%. The study’s findings reveal that this tool provides objective, reliable metrics that align closely with clinical evaluations, offering new pathways for personalized rehabilitation. 

How LPKF ProtoLaser U4 Enabled Precision and Performance 

The fabrication of the glove’s electronics was realized using the LPKF ProtoLaser U4, a UV laser system renowned for its precision and adaptability. Key contributions of the ProtoLaser U4 include: 

  • High-Precision Patterning: The UV laser enabled intricate designs for the glove’s flexible printed circuit board, ensuring seamless electrical interconnections. 

  • Material Compatibility: From copper to thin polyimide layers, the ProtoLaser U4 handled diverse materials essential for the glove’s functionality.  

  • Rapid Prototyping: Accelerated fabrication timelines supported iterative development, enabling researchers to optimize the design efficiently.  

  • By integrating advanced laser technology, the ProtoLaser U4 demonstrated LPKF’s commitment to performance and pioneering innovations, fulfilling the promise of "Tomorrow’s Technology Today."  

Collaboration Across Borders: A Testament to Partnership 

The glove was developed by a multidisciplinary team led by Yu Li, Junyi Yin, Shuoyan Liu, and Jun Chen, spanning institutions like Changchun University, UCLA, and the National University of Singapore. This partnership underscores the importance of global collaboration in tackling medical challenges, with LPKF’s systems providing a critical foundation for success 


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Discover how LPKF’s ProtoLaser U4 can transform your research and prototyping needs. Visit the ProtoLaser U4 product page to learn more about its features. To explore the potential of LPKF solutions in your projects, contact us via our contact form or subscribe to our newsletter for updates on groundbreaking technologies. 

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